cultured astrocyte by Charmaine Szalay-Anderson

Live Cell Imaging

The vision of the Live Cell Imaging laboratory (LCI) is to drive innovative research using cutting edge optical imaging technology. We provide intensive training and education, advice and intellectual input for research relying on optical imaging and image analysis. We also develop new applications and test new technologies for the benefit of our research community. The level of support is tailored to the individual researcher and can range from access to microscopes to full research collaborations.

The banner image is a cultured astrocyte by Charmaine Szalay-Anderson.

Live Cell Imaging

The Live Cell Imaging laboratory was recently renovated thanks to a generous donation from Matt and Tara Brister. We thank them both for their continuous support of the Snyder Institute for Chronic Diseases.


Service Activities and Training

  • Access to optical imaging equipment
  • Basic to advanced microscopy training
  • Basic to advanced image analysis training
  • Surgery training

Research Activities

  • Feasibility studies
  • Pilot experiments
  • Novel application development
  • Long-term project support
  • Equipment, protocol design or modification
  • Software modification or design for image analysis or acquisition.

Key Areas of Research

Optical imaging applications for:

  • Live cells
  • Tissue and live mice in areas of immunology
  • Microbiology
  • Cell biology
  • Cancer
  • Infectious diseases
  • Chronic diseases.

Select Publications

  • Sharma R et al.FRNK negatively regulates IL?4?mediated inflammation. J Cell Sci. 2015;128(4):695-705.
  • Jonkman JE et al. An introduction to the wound healing assay using live-cell microscopy. Cell Adh Migr. 2014;8(5):440-451.
  • D'Mello C et al. P-selectin-mediated monocyte-cerebral endothelium adhesive interactions link peripheral organ inflammation to sickness behaviors. J Neurosci. 2013; 33(37):14878?88.
  • Shi M et al. Real?time in vivo imaging of fungal migration to the central nervous system. Cell Microbiol. 2012 14(12):1819-1827.


Pina Colarusso, PhD
Scientific Director
HS-2822A: 403.220.6111